ankara šocuk endokrin ankara šocuk endokrinoloji doktorlarř
─░K─░ FARKLI GA─░TADA G─░ZL─░ KAN TEST─░N─░N GE├çERL─░L─░K Y├ľN├ťNDEN KAR┼×ILA┼×TIRILMASI - COMPARE of VALIDITY of TWO DIFFERENT FAECAL OCCULT BLOOD TESTS | I┼č─▒ktekin Atalay | Eski┼čehir T├╝rk D├╝nyas─▒ Uygulama ve Ara┼čt─▒rma Merkezi Halk Sa─čl─▒─č─▒ Dergisi (ISSN:2564-6311)

─░K─░ FARKLI GA─░TADA G─░ZL─░ KAN TEST─░N─░N GE├çERL─░L─░K Y├ľN├ťNDEN KAR┼×ILA┼×TIRILMASI - COMPARE of VALIDITY of TWO DIFFERENT FAECAL OCCULT BLOOD TESTS

Burcu I┼č─▒ktekin Atalay, G├╝ls├╝m ├ľzt├╝rk Emiral, Burhanettin I┼č─▒kl─▒, ─░brahim ├ľzkan Alata┼č, Selma Metinta┼č, Muhammed Fatih ├ľns├╝z

├ľz


├çal─▒┼čman─▒n amac─▒, sahada gizli kan tespiti i├žin ├Ânerilen gaitada gizli kan testinin, referans bir gaitada gizli kan testi ile ge├žerlilik y├Ân├╝nden kar┼č─▒la┼čt─▒r─▒lmas─▒d─▒r. Eski┼čehir Osmangazi ├ťniversitesi T─▒p Fak├╝ltesi Biyokimya laboratuvar─▒na g├Ânderilen gastrointestinal sistemde kanama ┼č├╝phesi olan hastalar─▒n gaitalar─▒ ├╝zerinde yap─▒lan metadolojik bir ├žal─▒┼čmad─▒r. ├ťniversite polikliniklerine ba┼čvuran hastalardan gastrointestinal sistemde kanama ┼č├╝phesi olan 101 hasta ├žal─▒┼čma grubunu olu┼čturdu. Her gaita numunesine s─▒ra ile sahada kullan─▒lan immunokimyasal gaitada gizli kan testi, ard─▒ndan referans immunokimyasal gaitada gizli kan testi yap─▒ld─▒. Biyokimya laboratuvar─▒nda kullan─▒lan gaitada gizli kan testi referans test olarak kabul edildi. Sahada kullan─▒lan gaitada gizli kan testi 12(%11.9) hastada pozitif iken, referans gaitada gizli kan testi ise 26(%25.7) hastada pozitifdir. Sahada kullan─▒lan testte 89(%88.1) hasta negatif iken, referans gaitada gizli kan testinde 75(%74.2) hasta negatif idi. ─░ki test aras─▒nda ileri derecede uyum bulundu (p< 0.001). Sahada kullan─▒lan gaitada gizli kan testinin, referans gaitada gizli kan testine g├Âre sensitivitesi %46, spesifitesi %100, pozitif prediktif de─čer %100 ve negatif prediktif de─čer ise %84 olarak hesapland─▒. ├çal─▒┼čmada sahada kullan─▒lan gaitada gizli kan testinin spesifitesi y├╝ksek ancak testin sensitivitesi d├╝┼č├╝k olarak hesapland─▒. Taramalarda kullan─▒lan testlerin hem duyarl─▒l─▒─č─▒n─▒n hem de ├Âzg├╝ll├╝─č├╝n├╝n y├╝ksek olmas─▒ gerekmektedir. Gaitada gizli kan testinin de─čerlendirilmesi i├žin geni┼č ├Ârneklem gruplar─▒nda ├žal─▒┼čma tekrar─▒na ihtiya├ž vard─▒r.

Anahtar kelimeler: Gaitada gizli kan testi, Metadolojik ├žal─▒┼čma, Sensitivite, Spesifite, Tarama

COMPARE of VALIDITY of TWO DIFFERENT FAECAL OCCULT BLOOD TESTS

The aim of the study is to compare the validity of faecal occult blood test, with a reference faecal occult blood test. This study is a methodological study conducted on the patientsÔÇÖ gaita who had suspected bleeding in the gastrointestinal system which were sent to Biochemistry Laboratory of Eskisehir Osmangazi University Faculty of Medicine. A total of 101 outpatients who had suspected bleeding in the gastrointestinal tract were included in the study. Each gaita sample analyzed by a immunochemical faecal occult blood test used was performed, and then also analyzed by a reference immunochemical faecal occult blood test. The faecal occult blood test used in the biochemistry laboratory was accepted as a reference test. While 12 (11.9%) of the faecal occult blood test used in the screening was positive, 26 (25.7%) were found positive by the reference faecal occult blood test. While 89(88,1%) of the faecal occult blood test used in the screening was negative, in the reference faecal occult blood test, 75(74.2%) were negative. There was a good concordance between the two tests (p< 0.001). According to the faecal occult blood test in the reference, the sensitivity of the faecal occult blood test used in the screening was 46%, the specificity was 100%, positive predictive value was 100% and negative predictive value was 84%. In the study, the specificity of the faecal occult blood test used in the screening was high but the sensitivity of the test was low. The sensitivity and specificity of the tests used in the sceening should be high. There is a need to repeat studies in large sample groups to evaluate the faecal occult blood test

Keywords: Faecal occult blood test, Metadological study, Sensitivity, Specificity, Screening


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ARTICLE 2

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